
Cover Illustration: Crystal structure of the PAZ domain of human eIF2C1 protein in complex with a 9-mer siRNA-like RNA duplex of deoxynucleotide overhang (Protein Data Bank code: 1si2; Ma, J.B., Ye, K., and Patel, D. 2004. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429: 318-322). Image details: protein: solid surface, chain-specific coloring; RNA: ribbon-plate representation, A—red, U—magenta, C—blue, G—green). The image was generated with the Accelrys Discovery Studio Visualizer. Cover image provided by the Jena Library of Biological Macromolecules (JenaLib) (www.fli-leibniz.de/IMAGE.html).